The rumors surrounding Jennifer Aniston, Brad Pitt and Angelina Jolie have been swirling non-stop since the “Mr. & Mrs. Smith” stars opt for divorce. According to reports, the “Allied” actor started contacting Justin Theroux’s wife since he had split with the “Maleficent” star.

And to stop all the bad accusations for the two, “Friends” alum’s best friend Chelsea Handler defended her friend in an interview with You magazine. Aside from opening up about their longtime friendship, she also talked about her connection with the ex-couple.

Handler defending Aniston over Jolie, Pitt rumors

Handler insisted that Anniston doesn’t care with the issues Jolie and Pitt have been going through. “I don't think Jen cares about what's going on, and it's crazy that people think she does,” she told the publication. “As if she's sitting around caring about [Jolie]. I know I don't.”

A diss to Jolie

This is not the first time that Handler dissed Jolie since she got married and had a long-time relationship with Pitt. To recall, in one of the episodes of her show “Chelsea” on Netflix, she took aim at the “Salt” actress. The 42-year-old comedienne explained that the problem Jolie and Pitt might have been facing was the latter’s alleged heavy drinking and smoking too much weed.

Now, she questioned why he needed to self-medicate.

She then had a hint that he might be wishing to spend the last 12 years of his life enjoying at the Lake Como with his friends George Clooney and Matt Damon, instead of staying in their home with a lot of kids speaking different languages. The television host talked about the former couple's six children – Maddox (15), Pax (13), Zahara (12), Shiloh (10), and twins Vivienne and Knox (8) – that have different ethnicities.

Anniston’s colorful love life

To recall, Aniston and Pitt were married from July 2000 to October 2005 as he had a relationship with Jolie. Since then, “The Brea-Up” star had been linked to different famous stars, like her co-star Vince Vaughn and John Mayer. But, she then met Theroux and got married in August 2015.