Even before Donald Trump became a candidate for president he had engaged in a war of worlds with high-profiled individuals. In the years before he announced his candidacy for president, Trump was involved in a feud with actress and talk show host Rosie O'Donnell, which has only escalated over the last year and a half.

Rosie on Trump

During the first Republican debate of the 2016 presidential election, Donald Trump was grilled on his questionable history with women, with former Fox News host and debate moderator Megyn Kelly pushing the billionare real estate mogul hard on the issue.

After Kelly accused Trump of referring to women as "dogs" and "pigs," the former host of "The Apprentice" humorously fired back and replied, "Only Rosie O'Donnell." Since then, O'Donnell has been vocal in her opposition to Trump, which continued on her Twitter feed with an interaction with First Lady Melania Trump, as reported by Raw Story on March 31.

With Women's History Month coming to a close, Melania Trump has been a bit more active, including in her use of social media. on Tuesday, Melania posted a quote to her Twitter feed that reads, "I urge you to not be afraid to fail - as failure will never have the power to define you, as long as you learn from it." In response, Rosie O'Donnell called for the First Lady to take her son and leave Donald Trump.

"Which is y u need to divorce him," Rosie O'Donnell wrote in response on Twitter, while adding, "take ur son n parents and FLEE." This isn't the first time O'Donnell has commented on the Trump family, as she came under fire late last year after suggesting that 10-year-old Barron Trump might be suffering from autism.

The former co-host on "The View" would end up walking back her remarks, and clarified that she was only curious due to one of her own children being autistic.

Moving forward

As expected, neither Donald or Melania Trump offered a response to Rosie O'Donnell, which doesn't come as a surprise since the president has gone cold when it comes to his criticism about people in the entertainment field.

Since being sworn into office, Trump has limited his criticism of Hollywood stars, with the lone exception being of former California governor and host of "The Celebrity Apprentice," Arnold Schwarzenegger.