Oprah Winfrey is scheduled to be on CBS's "The Talk" on Monday, April 17. The media mogul will be interviewed for the first time by Julie Chen, Sara Gilbert, Sharon Osbourne, Aisha Tyler and Sheryl Underwood. Everyone is expecting this to be one of their best shows.

The interview

It is a good thing that Oprah is the only guest scheduled for the whole hour on CBS "The Talk" because there is so much going on in Oprah's life that she has lots of things to talk about and a lot of projects to promote.

The actress will no doubt talk about her new HBO film, "The Immortal Life of Henrietta Lacks" that will premiere five days later on April 22.

The movie is based on a true story in which Oprah is an executive producer and has a starring role as Deborah Lacks, the daughter who never knew her mother. Henrietta's cancerous cells were used in 1951 without her knowledge.

Winfrey will have enough time to talk about her upcoming role as a special correspondent on "60 Minutes." She has been a fan of the news program since her reporting days. The CBS news magazine is in its 49th season and averages about 14 million viewers each week. Producers have already said that Winfrey will be an asset to their top-rated show. Since Oprah will report on exclusive news, there is no set a date for her to appear since she will not be a regular.

The queen of talk shows will also share some things people didn't know about her own talk show that lasted for 25 years.

Top Videos of the Day

She will take the hosts and viewers behind the scenes of "The Oprah Winfrey Show" for some interesting details.

Oprah has been so busy that she will not run out of things to talk about. She might give an update on her involvement with Weight Watchers. She and her friend, Tyler Perry, along with Tracey Morgan have teamed up to lend their voices to a new animated Christmas film about the birth of Jesus. "The Star" will be in theaters nationwide on November 10.

Role reversals

Usually, Oprah is the one interviewing people. However, this time she will be the one who is interviewed. The co-hosts of "The Talk" are expected to share asking the questions. There will be enough time for the 63-year-old special guest to answer their questions and even give additional information about her many upcoming projects.

With so much to talk about, there will probably not be a dull moment. Because of the personalities of the hosts, expect to be enlighted by what they say. Watch "The Talk" on CBS Monday, April 17.