Donald Trump's pick to lead the CIA, Gina Haspel, is facing opposition from some in the Republican Party, including Sen. John McCain. After a story broke reporting that a top Trump staffer mocked McCain's opposition by poking fun at his brain cancer, the Arizona senator's wife spoke out.

McCain's reaction

It's been well-documented that Donald Trump and Republican Arizona Sen. John McCain don't see eye to eye. It started during the early days of the 2016 presidential campaign when Trump said that McCain was "not a war hero" because he was captured during the Vietnam War, infamously saying, "I like people who weren't captured." Since then, McCain has not held back his thoughts on Trump, with the president taking shots at the senator from time to time.

Fast forward to present day and McCain is fighting brain cancer, but is still keeping up to date on current events, and is opposed to Gina Haspel, Trump's pick to lead the CIA due to her support of torture.

A report broke on May 10 that Trump special assistant Kelly Sadler mocked John McCain over his opposition to Gina Haspel [VIDEO], allegedly saying, "It doesn’t matter, he’s dying anyway." In a tweet sent out Thursday night, Cindy McCain gave her thoughts, tweeting to Sadler, "May I remind you my husband has a family, 7 children and 5 grandchildren." Additional reports note that Sadler called the senator's daughter, Meghan McCain, and got into a heated discussion over what was reportedly said.

Twitter erupts

In response to the news of Kelly Sadler's comments about John McCain, social media quickly went viral [VIDEO]. "Our taxes pay her damn salary. Oh, one more thing. Kindly, don’t ever talk to me again about the cruelty of a 'smoky-eye' joke," CNN contributor Ana Navaro tweeted.

"Kelly Sadler is an example of the stain this administration is upon America," a Twitter user wrote.

"Kelly Sadler is exactly what the GOP have become. She is who they are. She is a disgrace," another tweet added. "What pathetic behavior. Your comment was cruel. Cruel and completely lacking in even a minimal amount of regard or respect for another human being. You could learn a lot about courage, character, humility and empathy from John McCain.," yet another tweet went on to read.

"You're a disgrace. Apologize to the entire McCain family, then resign," a social media user wrote. WH Asst. Kelly Sadler proved to be even more Deplorable than most when during a discussion on Sen. John McCain’s opposition to Gina Haspel, she said, “It doesn’t matter, he’s dying anyway.” I’m willing to bet she’s a regular church goer, probably praying for McCain’s death.," a follow-up tweet read.