The decade-long feud between Donald Trump and Rosie O'Donnell has taken an absurd turn, with the 55-year-old comedian begging Melania Trump to get a divorce, grab her family, and head for the hills.

O'Donnell's bizarre suggestion came as a response to a tweet posted by the First Lady on March 29, in which Melania Trump urged her followers to never be afraid to fail. "I urge you to not be afraid to fail -- as failure will never have the power to define you, as long as you learn from it," tweeted the former fashion model.

O'Donnell replied to the First Lady's message of inspiration with a tweet of her own: "which is y u need to divorce him - take ur son n parents and FLEE."

A brief history of the Trump-O'Donnell feud

Rosie O'Donnell's back-and-forth battle with Donald Trump dates back to December of 2006, when the former co-host of ABC's "The View" blasted the future commander-in-chief over his Miss USA pageant. Putting on an impersonation of Trump by mimicking his voice and combing over her hair, O'Donnell joked about Trump's failed marriage and his alleged affairs.

Trump responded by threatening legal action and taking a few jabs of his own. "I’ll most likely sue her for making those false statements -- and it’ll be fun," said Trump to People Magazine in December of 2006.

"Rosie’s a loser. A real loser. I look forward to taking lots of money from my nice fat little Rosie.”

Trump and O'Donnell have been squabbling with each other ever since, although the feud simmered on the backburner in recent years with both parties only taking occasional potshots at each other -- until Trump decided to run for president.

O'Donnell's Trump-trolling obsession

The feud was reignited during the Republican primary debate in August of 2015, when moderator Megyn Kelly questioned Donald Trump about calling women names like "pigs" and "slobs."

"Only Rosie O'Donnell," Trump shot back.

Since the election, trolling the Trumps has become something of an obsession for O'Donnell.

In November of 2016 she came under fire after suggesting on Twitter that Donald Trump's 10-year-old son, Barron, might be autistic. O'Donnell later apologized for the tweet. In March, O'Donnell led a protest prior to the president's first address to Congress, urging lawmakers to impeach President Trump over his alleged connections with Russia.