The NFL season kicked off with a fantastic game between the Panthers and the Broncos that ended with a Broncos victory after a missed field goal. The betting line for the game was shifted from what was originally about an even line to a line that favored the Panthers by 3 on the road.

Any savvy better knew that people betting on the Panthers weremaking amistake and continued to place bets on the Broncos, who easily covered the spread against the Panthers at home. In this article, I'm going to take a look at this week's slate of NFL games and make threepredictions aboutsomegames bettors should be targeting in week 1.

1. Best Bet: Saints (-1) vs. Raiders

This game is projected to be one of the highest scoring games of the week with an over/under total of 52 points. I wouldn't be surprised to see the game go over that total with stars like Amari Cooper in the fold, but I like the Saints to win their week 1 game outright even more.

The Raiders have a significantly improved offense with stars like Derek Carr, Latavius Murray, and Amari Cooper, but they are playing a Saints team that doesn't usually lose at home. Additionally, the Raiders defense isn't great, and Drew Brees won't have much trouble picking them apart with weapons like Brandin Cooks and Coby Fleener at his disposal. Expect the Saints to come away with a victory in a shootout.

2. Colts (-3) vs. Lions

The Colts originally opened as 6 point favorites against a Lions team that looks far less scary without Calvin Johnson around. Golden Tate doesn't exactly strike fear into the opposition, and Ameer Abdullah fumbles way too much to be an effective starting running back.

It's really hard for me to believe that the Lions will have an effective offense, even if the Colts are missing a bunch of cornerbacks. I trust Andrew Luck and the Colts to shut down a weak Lions offense and pick up the win in week 1.

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3. Vikings vs. Titans Over 40.5

Really? 40.5 points is an actual line that was just set in an NFL game? To go under that total, both teams would have to average just five points in a quarter. I realize that Shaun Hill is starting for the Vikings, but I don't think that the total will be this low.

If anything, the defenses in this game will make the point total rise when mistakes and turnovers lead to more points for both sides. This will be a hard fought week 1 game, but it should get over one of the lowest point totals I have seen in a long time.

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