Fans of "American Horror Story" were kept in the dark prior to the premiere episode of the fan-favorite FX series by creators Ryan Murphy and Brad Falchuk, who kept the premise of season six tightly wrapped. Now it seems that they had a good reason to keep their plot twists quiet; the new storylines are ripped right from true events in American history.

Murphy and Falchuk have always teased storylines and cast photos prior to the debut of the series. When they failed to do so this season, fans wondered just what the premise of the show would be for season six.

The latest season seems to be stripped right from the headlines of the past as the mysterious storyline involving Matt and Shelby (Andre Holland and Lily Rabe) continues to unfold in the season titled "My Roanoke Nightmare."

What are some of the real-life mysteries 'American Horror Story' is referencing?

The season has revealed thus far that Matt and Shelby have endured a traumatic experience in their life, forcing them to move to Roanoke. The season has unfolded in such a way that it is told through flashbacks and re-enactments of past events.

These flashbacks star Emmy-winner Sarah Paulson and Academy Award winner-Cuba Gooding, Jr.

According to a story posted by Movie Pilot, the show will be rife with historical references to several true horror stories. The use of the town of Roanoke is significant to the series. Roanoke was originally settled by the English in 1587 and the original colonists mysteriously disappeared without a trace. The disappearance of the colony is one America’s biggest unsolved mysteries.

How do these mysteries connect to 'American Horror Story' characters Matt and Shelby?

Movie Pilot revealed that there have been several references to the colonist's disappearance in the series first episodes. One major plot point is the farmhouse where Matt and Shelby reside, which continues to be plagued by strange instances, including Shelby being attacked by a group of people who wore colonial period clothing.

Also cited in the series was a creepy reference including two women wearing nurse's outfits who murder a patient. Movie Pilot refereed to these characters as possibly a dramatization of two women who were convicted of murdering patients at a nursing home many years ago.

The horror continues when "American Horror Story: Ronaoke" airs Wednesdays at 10 p.m. EST on FX.

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