Cam Newton and the Carolina Panthers visit the #San Francisco 49ers in Week 1 of the 2017 NFL schedule. For Newtown and company, it will be a fresh start after an unsuccessful campaign last season. The team followed up their failure to win the #Super Bowl against the Denver Broncos by failing to qualify for the playoffs last season. However, this season there are expectations that Newton regains his footing as one of the top stars in the league. Here's the latest Panthers vs. 49ers game preview with NFL matchup odds, game time, channel and how to watch it live streaming online.

NFL game preview

For the 2016 NFL season, the Carolina Panthers finished at a disappointing 6-10 overall, which was dead last in the NFC South.

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The Atlanta Falcons emerged from the division as the top team in the NFL and challenged New England in the Super Bowl. Carolina failed to make the postseason after a trip to the Super Bowl the season prior behind superstar quarterback Cam Newton. The Panthers' QB will be back with a brand new focus towards leading his team towards success in 2017. He'll look to Kelvin Benjamin in today's game to exploit coverage issues with the 49ers defense.

While expectations are for more wins this season, that may not amount to much for the San Francisco 49ers. However, they now have their quarterback situation somewhat resolved and will be under a brand new head coach with Kyle Shanahan having joined the team. Shanahan comes to the team after being offensive coordinator for the Falcons and will become the team's fourth coach in four years now.

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He'll try to lead his newest team to an upset win to start their season at 1-0 but Cam Newton and Ron Rivera have other plans.

The Carolina Panthers enter this matchup as five-point favorites on the spread. They also carry a moneyline price of -240. Meanwhile, the 49ers are +190 underdogs at home. Sunday's over/under points total for this game is 45.5 points as of this report.

How to watch live on TV, online

The Carolina Panthers vs. San Francisco 49ers game gets started at approximately 4:25 p.m. Eastern Time on Sunday evening. Live television coverage of this game will be made available through the FOX network and their affiliated channels around the United States. Certain regions of the country will see this game while others may see the Seahawks vs. Packers game.

For live streaming, fans in the regions showing this game that have Fox as part of their cable or TV package may be able to use the FoxSports Go website or mobile apps to see a #live stream feed. In addition, the NFL Game Pass and Verizon NFL Mobile subscription-based services should have live coverage of the game for customers, although availability may be limited by region or other factors.