The results of research by British scientists published in the journal Nature are estimated to be a milestone in the study of breast cancer and are based on knowledge of the genetic mutations that affect the occurrence of this type of cancer the BBC reported on Monday. In the largest study ever conducted, scientists are trying to discover the causes of this disease. They first need to understand what in our genetic code went in the wrong direction because healthy tissue converts into carcinogenic ones. A large international team of scientists studied all three billion pieces that make up the human genetic code in breast cancer. They found 93 sets of genes that, when mutated, can cause the development of tumors.

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Some of the genes were discovered earlier, but the scientists hope that this is the final list. Professor Mike Stratton, director of the Institute Sanger of Cambridge who led the research says that this is a turning point in cancer research.

Women lack of health care on the causes of cancer

"The people genome has about 20,000 genes. It seems that we now have a complete picture of breast cancer. In fact, we know that there are 93 groups of genes that normally healthy breast tissue, after mutating convert to carcinogenic, and this is very important information," Stratton said. Tghe list was delivered to the universities, pharmaceutical companies, and biotechnology companies to start work on the development of medications because "new therapy should target just these genes and their proteins." He went on to say that, 'We already have a number of medications that have been developed in the last 15 years and we know how to act.

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One is Herceptin, which is used in patients with specific mutations." It is anticipated that new drug developments for cancer treatment could take up to ten years.

The bad information is that about 60 percent of the mutations that cause breast cancer are detected in only ten genes, and for so rare mutations there probably wont be enough money. Gene mutation leaves 'scars' in our DNA, and that is how the British scientists managed to identify 12 types of damage caused by mutations in the breast tissue. Some are linked to  family heritage, but most of them can not be explained.

Research hoped to reduce risk of developing cancer

'In the future, we would like to focus on the profiling of individual cancer genomes in order to implement the most successful treatment for a person who is diagnosed with breast cancer. This is a step forward in a personalized approach to cancer treatment,"s aid one of the participating research Dr. Serena Nik-Zainal. The study "allows scientists to better understand the complete picture of the genetic changes" in the origin of breast cancer and could be an important step forward in the development of new smart medications and result in a larger number of patients which will successfully beat breast cancer, said Dr. Emma Smith of Britain's Institute of Cancer Research .

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